Literature / Library
Library
8 pictures and 45 papers on the myelocyte: the pictures by method, the papers by section. A picture opens large on a click and goes to its paper on a second. Every PMID myelo.site cites (138) is checked against PubMed for retractions at each build: none found.
Electron microscopy 1
Normal neutrophils in (A)-(D), showing developmental stages of myeloblasts: myeloblasts (A), promyelocytes (B), myelocytes (C) to segmented granulocytes (D), x5k. (E)-(H) Positive myeloperoxidase reactivity of primary granules, x5k.
Ru YX, Dong SX, Liu J, Eyden B. Development of Auer bodies from giant inclusions associated with rough endoplasmic reticulum in acute promyelocytic leukemia. Blood Sci. 2023;5:111-117. PMID: 37228776 · CC BY 4.0
Stained sections and smears 6
Myelocyte on bone marrow preparation, Giemsa stain. Normal morphology: round nucleus, pale cytoplasm.
Prof. Osaro Erhabor · CC BY-SA 4.0
Acute promyelocytic leukemia (APL): Wright-Giemsa and MPO staining of promyeloblasts with Auer rods (arrows). The myelocyte's antecedent stage, arrested in APL.
Ru YX, Dong SX, Liu J, Eyden B. Development of Auer bodies from giant inclusions associated with rough endoplasmic reticulum in acute promyelocytic leukemia. Blood Sci. 2023;5:111-117. PMID: 37228776 · CC BY 4.0
Trilineage hematopoiesis in bone marrow: erythroid, myeloid, and megakaryocytic precursors including myelocyte-stage cells.
Mikael Haggstrom M.D. · CC0
(A) Bone marrow cytomorphology by bone marrow aspirate smear. (B) Karyotype of bone marrow. (C) FISH probe detection of myeloid sarcoma biopsies. (D) FISH probe detection of bone marrow aspirate.
Du Y, Yang K, Ling Y, Zhang Y, Gong Y. A case report of acute promyelocytic leukemia with myeloid sarcoma of the lumbar spine and literature review. Front Med (Lausanne). 2024;11:1507716. PMID: 39911670 · CC BY
Radiologic, histopathologic, cytologic, and bone marrow findings (A) Contrast-enhanced chest CT demonstrates a large mass in the right hilar region (red arrow), accompanied by a large right-sided malignant pleural effusion (yellow arrow) and significant pleural thickening (blue arrow). (B) Immunohistochemical staining of the pleural biopsy specimen reveals strong nuclear positivity for TTF-1 in tumor cells (brown staining, red arrows), confirming an origin of lung adenocarcinoma. (C) Pleural effusion cytology (H&E stain) reveals clusters of adenocarcinoma cells against a hemorrhagic background, exhibiting enlarged, hyperchromatic nuclei and marked atypia (blue and yellow arrows). (D) Bone marrow smear demonstrates marked granulocytic hyperplasia. Myeloblasts (red arrow), plasma cells (blue arrow), and mature eosinophils (yellow arrow) are visible, features consistent with a paraneoplastic leukemoid reaction. CT: computed tomography; TTF-1: thyroid transcription factor-1; H&E: hematoxylin and eosin
Duan Y, Yang Y, Yu H, Zhang C, Wang Y, Ruan M et al. Paraneoplastic Leukemoid Reaction in Lung Adenocarcinoma With Multi-lineage Granulocytic Abnormalities and Eosinophilic Pleural Effusion. Cureus. 2025;17:e97404. PMID: 41431550 · CC BY 4.0
Bone marrow aspirate, showing normal trilineage hematopoiesis: myelomonocytic cells (an eosinophil myelocyte marked), erythroid cells (an orthochromatic erythroblast marked), and megakaryocytic cells.
Mikael Haggstrom M.D. · CC0
Figures and diagrams 1
Granulocytic maturation series: myeloblast through segmented neutrophil, with nucleus shape, size range, granule types, and N:C ratio. The myelocyte stage (center, outlined).
myelo.site illustration, after Bainton DF, Ullyot JL, Farquhar MG. The development of neutrophilic polymorphonuclear leukocytes in human bone marrow. J Exp Med. 1971;134:907-34. PMID: 4106490 · CC BY-SA 4.0
Publications 45
Filed by MeSH heading or keyword; each paper says which one matched. The Publications page holds the dated feed.
- Wang H, Hu N, Barovic M, Pan B, Cheng G, Li X, et al. Exacerbation of inflammatory bone loss in TET2-driven clonal hematopoiesis. J Immunol. 2026;215:vkag248. PMID: 42753712. research paper
- Tang G, Li M, Cheng J, Wang Z, Wang G, Shi J, et al. Pulmonary effect of 2D MXenes in mice: Immune cell responses and disrupted hematopoiesis. NanoImpact. 2026;43:100643. PMID: 42607808. research paper
- Babcock M, Lechner A, Drolet J, Agostini L, Weinstock R, Urao N. Dysregulated myelopoiesis and enhanced glutaminase-dependent neutrophil survival in preclinical obesity. Immunohorizons. 2026;10:vlag025. PMID: 42501750. research paper
- Kashatnikova DA, Gracheva AS, Kuzovlev AN, Salnikova LE. Genetic Architectures of Myeloid Dysregulation in Severe COVID-19. Viruses. 2026;18:604. PMID: 42357614. research paper
- Chattopadhyay D, Nitin N, Jaggers RM, Athmanathan B, Maremanda KP, Kanuri B, et al. Inflammasome-Primed Neutrophils Aggravate Atherosclerosis in Cigarette Smoking. Circ Res. 2026;139:e327714. PMID: 42267417. research paper
- Gutiérrez F, Vasile B, Ivir M, Alvarez S, Salva S. Mechanistic insights into postbiotic-induced myelopoiesis and immune recovery after chemotherapy. J Pharmacol Exp Ther. 2026;393:104934. PMID: 42202702. research paper
- Wong SQ, Hayashi K, Subel EJ, Huang YH, Gao H, Garcia HE, et al. Chemotherapy-induced activation of caspase-1 and IL-1α release by cancer cells remotely skews myelopoiesis to drive pro tumorigenic systemic neutrophil-dominant inflammation. Nat Commun. 2026;17:4724. PMID: 42009646. research paper
- Shi H, Ding ZC, Okoko OD, Wang X, Zhou G, Ye Y, et al. Chemotherapy-induced reactive myelopoiesis promotes expansion of immunosuppressive neutrophil-like monocytes in mice and humans. JCI Insight. 2026;11:e198360. PMID: 41945895. research paper
- Szarpak L, Jach ME, Skoczylas M, Radej S, Pruc M. Clonal Hematopoiesis (CHIP) in Pulmonary Embolism and CTEPH: Evidence, Mechanisms, and Risk Stratification. Int J Mol Sci. 2026;27:2750. PMID: 41898610. research paper
- Serra M, Akkaya S, Aglave M, Salma M, Bencheikh S, Hermand P, et al. IFN-I-Mediated Transcriptional Reprogramming Drives Myeloid-Skewed Hematopoiesis in Sickle Cell Anemia. Am J Hematol. 2026;101:1283-1301. PMID: 41853894. research paper
- Zhang H, Gu W, Yu K, Tu CL, Chang W, Liu J. Type 2 diabetes Reprograms Bone Marrow Hematopoiesis and Dysregulates Immune Signaling in Response to Stroke. bioRxiv. 2025. PMID: 41509336. research paper
- Duan Y, Yang Y, Yu H, Zhang C, Wang Y, Ruan M, et al. Paraneoplastic Leukemoid Reaction in Lung Adenocarcinoma With Multi-lineage Granulocytic Abnormalities and Eosinophilic Pleural Effusion. Cureus. 2025;17:e97404. PMID: 41431550. research paper
- Zhao N, Wang G, Long S, Chen Y, Gao J, Lv X, et al. Neutrophil Irg1/itaconate axis protects against experimental colitis by suppressing local inflammation and maintaining hematopoietic homeostasis. Mol Biomed. 2025;6:143. PMID: 41417165. research paper
- Serra M, Aglave M, Salma M, Akkaya S, Hermand P, Lefevre C, et al. IFN-I-Mediated Transcriptional Reprogramming Drives Myeloid-skewed Hematopoiesis in Sickle Cell Anemia. Res Sq. 2025. PMID: 41282081. research paper
- Ren XP, Chang ZL, Wang Y, Zhu HM, He WY. [Wip1 Phosphatase Regulates Hematopoietic Function in Mouse Spleen]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2025;33:1491-1498. PMID: 41234104. research paper
- Bashir HS, G C B, Rahman AA, Dong F. A critical role of the Erk1/2 downstream targets c-Fos, Egr-1, and Egr-2 in PU.1-driven monocyte development. J Leukoc Biol. 2025;117:qiaf159. PMID: 41206684. research paper
- Zhang Y, Huang Q, Zhang Y, Lu S, Li L, Yang S, et al. Single-cell profiling of long non-coding RNAs in the hematopoietic system. Blood Sci. 2025;7:e00240. PMID: 40979441. research paper
- Sefik E, Philbrick W, Zhang F, Agrawal K, Van Lee B, Sam J, et al. Humanization of CD47 enables development of functional human neutrophils via postirradiation remodeling of the bone marrow. Proc Natl Acad Sci U S A. 2025;122:e2426546122. PMID: 40956886. research paper
- Gelo O, Foncuberta MC, Sánchez Ávalos JC. [Normal and emergency hematopoiesis: current concepts and clinical implications]. Medicina (B Aires). 2025;85:810-821. PMID: 40793893. research paper
- Lee MKS, Cooney OD, Zhu Y, Zhang Y, Lin X, Onda DA, et al. Metformin suppresses atherosclerosis by dampening extramedullary myelopoiesis. Am J Physiol Endocrinol Metab. 2025;329:E420-E432. PMID: 40758579. research paper
- Kajihara K, Yan D, Seim GL, Little-Hooy H, Kang J, Chen C, et al. Systemic cytokines drive conserved severity-associated myeloid responses across bacterial and viral infections. Commun Biol. 2025;8:1096. PMID: 40702253. research paper
- Sukhina A, Queriault C, Roy S, Hall E, Rome K, Aggarwal M, et al. Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention. Elife. 2025;13:RP101670. PMID: 40662940. research paper
- Schell B, Zhao LP, M'Sibih I, Kalogeraki M, Kergaravat C, Lereclus E, et al. Modeling mesenchymal stromal cell support to hematopoiesis within a novel 3D artificial marrow organoid system. Sci Rep. 2025;15:23603. PMID: 40604201. research paper
- Daman AW, Antonelli AC, Redelman-Sidi G, Paddock L, Khayat S, Ketavarapu M, et al. Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity. Cancer Cell. 2025;43:1442-1459.e10. PMID: 40446799. research paper
- Rincon JC, Wang D, Polcz VE, Barrios EL, Dirain ML, Ungaro RF, et al. Innate immune training in the neonatal response to sepsis. Mol Med. 2025;31:159. PMID: 40307728. research paper
- Zhang R, Jin W, Wang K. Glycolysis-Driven Prognostic Model for Acute Myeloid Leukemia: Insights into the Immune Landscape and Drug Sensitivity. Biomedicines. 2025;13:834. PMID: 40299448. research paper
- Liarou M, Matthes T, Marchand-Maillet S. TimeFlow: A Density-Driven Pseudotime Method for Flow Cytometry Data Analysis. Cytometry A. 2025;107:233-247. PMID: 40111028. research paper
- Pan S, Tang H, Yao B, Tian G, Sun B, Hu Y, et al. Decoding the ontogeny of myeloid lineage diversity by cross-species and developmental analyses of hematopoietic progenitor atlases. Cell Rep. 2025;44:115406. PMID: 40057952. research paper
- Signoretto I, Calzetti F, Finotti G, Lonardi S, Balanzin C, Bianchetto-Aguilera F, et al. Uncovering two neutrophil-committed progenitors that immediately precede promyelocytes during human neutropoiesis. Cell Mol Immunol. 2025;22:316-329. PMID: 39939817. research paper
- Wang W, Chaudhary R, Szpendyk J, El Khalki L, Yousafzai NA, Chan R, et al. Kindlin-2-Mediated Hematopoiesis Remodeling Regulates Triple-Negative Breast Cancer Immune Evasion. Mol Cancer Res. 2025;23:450-462. PMID: 39918417. research paper
- Karela C, Tsagarakis NJ, Oudatzis G, Xanthopoulos V, Milaiou M, Nikolaou S, et al. FLAER Revealed Normally Expected Non-PNH FLAER-Dim Immature Myeloid Cells (CD117+/CD34-) In Bone Marrow Aspirates and Could Be Utilized as a Marker of Hierarchical Hematopoiesis. Int J Lab Hematol. 2025;47:228-235. PMID: 39478200. research paper
- Chen S, Fan Y, Wu Q, Zhang G, Wang Y, Li W, et al. Integrative Transcriptomic Analysis of Peripheral Blood Monocytes in Systemic Sclerosis and Shared Pathogenic Pathways in Autoimmune Diseases. Arch Med Res. 2025;56:103072. PMID: 39208548. research paper
- Du Y, Yang K, Ling Y, Zhang Y, Gong Y. A case report of acute promyelocytic leukemia with myeloid sarcoma of the lumbar spine and literature review. Front Med (Lausanne). 2024;11:1507716. PMID: 39911670. research paper
- Machado-Neto JA, Vicari HP, Lipreri da Silva JC, Carvalho MFL, Lima K. Emerging functions of FMNL1 in myeloid neoplasms: insights from bioinformatics to biological and pharmacological landscapes. Transl Cancer Res. 2024;13:6105-6116. PMID: 39697714. research paper
- Mou R, Ma J, Ju X, Wu Y, Chen Q, Li J, et al. Vasopressin drives aberrant myeloid differentiation of hematopoietic stem cells, contributing to depression in mice. Cell Stem Cell. 2024;31:1794-1812.e10. PMID: 39442524. research paper
- Nayak TK, Parasania D, Tilley DG. Adrenergic orchestration of immune cell dynamics in response to cardiac stress. J Mol Cell Cardiol. 2024;196:115-124. PMID: 39303854. research paper
- Jiang R, Lu Z, Wang C, Xiao J, Liu Q, Xu X, et al. Beta2 adrenergic receptor-mediated abnormal myelopoiesis drives neuroinflammation in aged patients with traumatic brain injury. Sci Adv. 2024;10:eadp5239. PMID: 39028822. research paper
- Shahbaz S, Rosero EP, Syed H, Hnatiuk M, Bozorgmehr N, Rahmati A, et al. Bipotential B-neutrophil progenitors are present in human and mouse bone marrow and emerge in the periphery upon stress hematopoiesis. mBio. 2024;15:e0159924. PMID: 39012145. research paper
- Wu L, Xia M, Wang C, Yan H, Gong X, Yin CC. Expression, Function, and Significance of Non B Cell-Derived Immunoglobulin in Haematological System. Adv Exp Med Biol. 2024;1445:179-188. PMID: 38967760. research paper
- Ruiz Pérez M, Maueröder C, Steels W, Verstraeten B, Lameire S, Xie W, et al. TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice. Cell Mol Immunol. 2024;21:807-825. PMID: 38839915. research paper
- Dolfi B, Gallerand A, Caillot Z, Castiglione A, Zair FN, Leporati L, et al. Sex-specific impact of psychosocial stress on hematopoiesis and blood leukocytes. Eur J Immunol. 2024;54:e2350851. PMID: 38803021. research paper
- Zhang Y, Zhou Y, Li X, Pan X, Bai J, Chen Y, et al. Small-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation. Stem Cell Res Ther. 2024;15:100. PMID: 38589882. research paper
- Kanuri B, Biswas P, Dahdah A, Murphy AJ, Nagareddy PR. Impact of age and sex on myelopoiesis and inflammation during myocardial infarction. J Mol Cell Cardiol. 2024;187:80-89. PMID: 38163742. research paper
- Ru YX, Dong SX, Liu J, Eyden B. Development of Auer bodies from giant inclusions associated with rough endoplasmic reticulum in acute promyelocytic leukemia. Blood Sci. 2023;5:111-117. PMID: 37228776. research paper
- Bainton DF, Ullyot JL, Farquhar MG. The development of neutrophilic polymorphonuclear leukocytes in human bone marrow. J Exp Med. 1971;134:907-34. PMID: 4106490. research paper
Signaling 9
Filed by MeSH heading or keyword; each paper says which one matched. The Signaling page holds the dated feed.
- Chattopadhyay D, Nitin N, Jaggers RM, Athmanathan B, Maremanda KP, Kanuri B, et al. Inflammasome-Primed Neutrophils Aggravate Atherosclerosis in Cigarette Smoking. Circ Res. 2026;139:e327714. PMID: 42267417. MeSH: Receptors, LDL
- Serra M, Akkaya S, Aglave M, Salma M, Bencheikh S, Hermand P, et al. IFN-I-Mediated Transcriptional Reprogramming Drives Myeloid-Skewed Hematopoiesis in Sickle Cell Anemia. Am J Hematol. 2026;101:1283-1301. PMID: 41853894. MeSH: Signal Transduction
- Ren XP, Chang ZL, Wang Y, Zhu HM, He WY. [Wip1 Phosphatase Regulates Hematopoietic Function in Mouse Spleen]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2025;33:1491-1498. PMID: 41234104. keyword: Wip1 phosphatase; spleen; hematopoiesis; inflammatory cytokines
- Bashir HS, G C B, Rahman AA, Dong F. A critical role of the Erk1/2 downstream targets c-Fos, Egr-1, and Egr-2 in PU.1-driven monocyte development. J Leukoc Biol. 2025;117:qiaf159. PMID: 41206684. MeSH: MAP Kinase Signaling System
- Kajihara K, Yan D, Seim GL, Little-Hooy H, Kang J, Chen C, et al. Systemic cytokines drive conserved severity-associated myeloid responses across bacterial and viral infections. Commun Biol. 2025;8:1096. PMID: 40702253. MeSH: Cytokines
- Nayak TK, Parasania D, Tilley DG. Adrenergic orchestration of immune cell dynamics in response to cardiac stress. J Mol Cell Cardiol. 2024;196:115-124. PMID: 39303854. MeSH: Receptors, Adrenergic
- Jiang R, Lu Z, Wang C, Xiao J, Liu Q, Xu X, et al. Beta2 adrenergic receptor-mediated abnormal myelopoiesis drives neuroinflammation in aged patients with traumatic brain injury. Sci Adv. 2024;10:eadp5239. PMID: 39028822. MeSH: Receptors, Adrenergic, beta-2
- Ruiz Pérez M, Maueröder C, Steels W, Verstraeten B, Lameire S, Xie W, et al. TL1A and IL-18 synergy promotes GM-CSF-dependent thymic granulopoiesis in mice. Cell Mol Immunol. 2024;21:807-825. PMID: 38839915. MeSH: Tumor Necrosis Factor Ligand Superfamily Member 15
- Zhang Y, Zhou Y, Li X, Pan X, Bai J, Chen Y, et al. Small-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation. Stem Cell Res Ther. 2024;15:100. PMID: 38589882. MeSH: Interleukin-3 Receptor alpha Subunit
Medications 11
Filed by MeSH heading or keyword; each paper says which one matched. The Medications page holds the dated feed.
- Tang G, Li M, Cheng J, Wang Z, Wang G, Shi J, et al. Pulmonary effect of 2D MXenes in mice: Immune cell responses and disrupted hematopoiesis. NanoImpact. 2026;43:100643. PMID: 42607808. MeSH: Hematopoiesis/drug effects
- Gutiérrez F, Vasile B, Ivir M, Alvarez S, Salva S. Mechanistic insights into postbiotic-induced myelopoiesis and immune recovery after chemotherapy. J Pharmacol Exp Ther. 2026;393:104934. PMID: 42202702. MeSH: Myelopoiesis/drug effects
- Wong SQ, Hayashi K, Subel EJ, Huang YH, Gao H, Garcia HE, et al. Chemotherapy-induced activation of caspase-1 and IL-1α release by cancer cells remotely skews myelopoiesis to drive pro tumorigenic systemic neutrophil-dominant inflammation. Nat Commun. 2026;17:4724. PMID: 42009646. MeSH: Neutrophils/drug effects
- Shi H, Ding ZC, Okoko OD, Wang X, Zhou G, Ye Y, et al. Chemotherapy-induced reactive myelopoiesis promotes expansion of immunosuppressive neutrophil-like monocytes in mice and humans. JCI Insight. 2026;11:e198360. PMID: 41945895. MeSH: Myelopoiesis/drug effects
- Serra M, Akkaya S, Aglave M, Salma M, Bencheikh S, Hermand P, et al. IFN-I-Mediated Transcriptional Reprogramming Drives Myeloid-Skewed Hematopoiesis in Sickle Cell Anemia. Am J Hematol. 2026;101:1283-1301. PMID: 41853894. MeSH: Anemia, Sickle Cell/drug therapy
- Zhao N, Wang G, Long S, Chen Y, Gao J, Lv X, et al. Neutrophil Irg1/itaconate axis protects against experimental colitis by suppressing local inflammation and maintaining hematopoietic homeostasis. Mol Biomed. 2025;6:143. PMID: 41417165. MeSH: Succinates/pharmacology
- Lee MKS, Cooney OD, Zhu Y, Zhang Y, Lin X, Onda DA, et al. Metformin suppresses atherosclerosis by dampening extramedullary myelopoiesis. Am J Physiol Endocrinol Metab. 2025;329:E420-E432. PMID: 40758579. MeSH: Metformin/pharmacology
- Kajihara K, Yan D, Seim GL, Little-Hooy H, Kang J, Chen C, et al. Systemic cytokines drive conserved severity-associated myeloid responses across bacterial and viral infections. Commun Biol. 2025;8:1096. PMID: 40702253. MeSH: Antibodies, Monoclonal, Humanized/therapeutic use
- Daman AW, Antonelli AC, Redelman-Sidi G, Paddock L, Khayat S, Ketavarapu M, et al. Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity. Cancer Cell. 2025;43:1442-1459.e10. PMID: 40446799. MeSH: Immunotherapy
- Zhang R, Jin W, Wang K. Glycolysis-Driven Prognostic Model for Acute Myeloid Leukemia: Insights into the Immune Landscape and Drug Sensitivity. Biomedicines. 2025;13:834. PMID: 40299448. keyword: drug sensitivity
- Mou R, Ma J, Ju X, Wu Y, Chen Q, Li J, et al. Vasopressin drives aberrant myeloid differentiation of hematopoietic stem cells, contributing to depression in mice. Cell Stem Cell. 2024;31:1794-1812.e10. PMID: 39442524. MeSH: Hematopoietic Stem Cells/drug effects
Disorders 31
Filed by MeSH heading or keyword; each paper says which one matched. The Disorders page holds the dated feed.
- Wang H, Hu N, Barovic M, Pan B, Cheng G, Li X, et al. Exacerbation of inflammatory bone loss in TET2-driven clonal hematopoiesis. J Immunol. 2026;215:vkag248. PMID: 42753712. MeSH: Periodontitis/pathology
- Tang G, Li M, Cheng J, Wang Z, Wang G, Shi J, et al. Pulmonary effect of 2D MXenes in mice: Immune cell responses and disrupted hematopoiesis. NanoImpact. 2026;43:100643. PMID: 42607808. MeSH: Lung/pathology
- Kashatnikova DA, Gracheva AS, Kuzovlev AN, Salnikova LE. Genetic Architectures of Myeloid Dysregulation in Severe COVID-19. Viruses. 2026;18:604. PMID: 42357614. MeSH: Inflammation
- Chattopadhyay D, Nitin N, Jaggers RM, Athmanathan B, Maremanda KP, Kanuri B, et al. Inflammasome-Primed Neutrophils Aggravate Atherosclerosis in Cigarette Smoking. Circ Res. 2026;139:e327714. PMID: 42267417. MeSH: Atherosclerosis
- Gutiérrez F, Vasile B, Ivir M, Alvarez S, Salva S. Mechanistic insights into postbiotic-induced myelopoiesis and immune recovery after chemotherapy. J Pharmacol Exp Ther. 2026;393:104934. PMID: 42202702. MeSH: Antineoplastic Agents
- Wong SQ, Hayashi K, Subel EJ, Huang YH, Gao H, Garcia HE, et al. Chemotherapy-induced activation of caspase-1 and IL-1α release by cancer cells remotely skews myelopoiesis to drive pro tumorigenic systemic neutrophil-dominant inflammation. Nat Commun. 2026;17:4724. PMID: 42009646. MeSH: Inflammation
- Shi H, Ding ZC, Okoko OD, Wang X, Zhou G, Ye Y, et al. Chemotherapy-induced reactive myelopoiesis promotes expansion of immunosuppressive neutrophil-like monocytes in mice and humans. JCI Insight. 2026;11:e198360. PMID: 41945895. MeSH: Lymphoma
- Szarpak L, Jach ME, Skoczylas M, Radej S, Pruc M. Clonal Hematopoiesis (CHIP) in Pulmonary Embolism and CTEPH: Evidence, Mechanisms, and Risk Stratification. Int J Mol Sci. 2026;27:2750. PMID: 41898610. MeSH: Pulmonary Embolism/pathology
- Serra M, Akkaya S, Aglave M, Salma M, Bencheikh S, Hermand P, et al. IFN-I-Mediated Transcriptional Reprogramming Drives Myeloid-Skewed Hematopoiesis in Sickle Cell Anemia. Am J Hematol. 2026;101:1283-1301. PMID: 41853894. MeSH: Anemia, Sickle Cell/pathology
- Zhang H, Gu W, Yu K, Tu CL, Chang W, Liu J. Type 2 diabetes Reprograms Bone Marrow Hematopoiesis and Dysregulates Immune Signaling in Response to Stroke. bioRxiv. 2025. PMID: 41509336. keyword: inflammation
- Duan Y, Yang Y, Yu H, Zhang C, Wang Y, Ruan M, et al. Paraneoplastic Leukemoid Reaction in Lung Adenocarcinoma With Multi-lineage Granulocytic Abnormalities and Eosinophilic Pleural Effusion. Cureus. 2025;17:e97404. PMID: 41431550. keyword: lung adenocarcinoma
- Zhao N, Wang G, Long S, Chen Y, Gao J, Lv X, et al. Neutrophil Irg1/itaconate axis protects against experimental colitis by suppressing local inflammation and maintaining hematopoietic homeostasis. Mol Biomed. 2025;6:143. PMID: 41417165. MeSH: Colitis/pathology
- Serra M, Aglave M, Salma M, Akkaya S, Hermand P, Lefevre C, et al. IFN-I-Mediated Transcriptional Reprogramming Drives Myeloid-skewed Hematopoiesis in Sickle Cell Anemia. Res Sq. 2025. PMID: 41282081. keyword: Inflammation
- Zhang Y, Huang Q, Zhang Y, Lu S, Li L, Yang S, et al. Single-cell profiling of long non-coding RNAs in the hematopoietic system. Blood Sci. 2025;7:e00240. PMID: 40979441. keyword: Leukemia
- Gelo O, Foncuberta MC, Sánchez Ávalos JC. [Normal and emergency hematopoiesis: current concepts and clinical implications]. Medicina (B Aires). 2025;85:810-821. PMID: 40793893. MeSH: Inflammation
- Lee MKS, Cooney OD, Zhu Y, Zhang Y, Lin X, Onda DA, et al. Metformin suppresses atherosclerosis by dampening extramedullary myelopoiesis. Am J Physiol Endocrinol Metab. 2025;329:E420-E432. PMID: 40758579. MeSH: Atherosclerosis
- Kajihara K, Yan D, Seim GL, Little-Hooy H, Kang J, Chen C, et al. Systemic cytokines drive conserved severity-associated myeloid responses across bacterial and viral infections. Commun Biol. 2025;8:1096. PMID: 40702253. MeSH: Bacterial Infections
- Sukhina A, Queriault C, Roy S, Hall E, Rome K, Aggarwal M, et al. Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention. Elife. 2025;13:RP101670. PMID: 40662940. MeSH: Disease Susceptibility
- Daman AW, Antonelli AC, Redelman-Sidi G, Paddock L, Khayat S, Ketavarapu M, et al. Microbial cancer immunotherapy reprograms hematopoiesis to enhance myeloid-driven anti-tumor immunity. Cancer Cell. 2025;43:1442-1459.e10. PMID: 40446799. MeSH: Urinary Bladder Neoplasms
- Zhang R, Jin W, Wang K. Glycolysis-Driven Prognostic Model for Acute Myeloid Leukemia: Insights into the Immune Landscape and Drug Sensitivity. Biomedicines. 2025;13:834. PMID: 40299448. keyword: acute myeloid leukemia
- Signoretto I, Calzetti F, Finotti G, Lonardi S, Balanzin C, Bianchetto-Aguilera F, et al. Uncovering two neutrophil-committed progenitors that immediately precede promyelocytes during human neutropoiesis. Cell Mol Immunol. 2025;22:316-329. PMID: 39939817. keyword: Chronic myeloid leukemia
- Wang W, Chaudhary R, Szpendyk J, El Khalki L, Yousafzai NA, Chan R, et al. Kindlin-2-Mediated Hematopoiesis Remodeling Regulates Triple-Negative Breast Cancer Immune Evasion. Mol Cancer Res. 2025;23:450-462. PMID: 39918417. MeSH: Triple Negative Breast Neoplasms
- Karela C, Tsagarakis NJ, Oudatzis G, Xanthopoulos V, Milaiou M, Nikolaou S, et al. FLAER Revealed Normally Expected Non-PNH FLAER-Dim Immature Myeloid Cells (CD117+/CD34-) In Bone Marrow Aspirates and Could Be Utilized as a Marker of Hierarchical Hematopoiesis. Int J Lab Hematol. 2025;47:228-235. PMID: 39478200. MeSH: Bone Marrow Cells/pathology
- Chen S, Fan Y, Wu Q, Zhang G, Wang Y, Li W, et al. Integrative Transcriptomic Analysis of Peripheral Blood Monocytes in Systemic Sclerosis and Shared Pathogenic Pathways in Autoimmune Diseases. Arch Med Res. 2025;56:103072. PMID: 39208548. MeSH: Scleroderma, Systemic/pathology
- Du Y, Yang K, Ling Y, Zhang Y, Gong Y. A case report of acute promyelocytic leukemia with myeloid sarcoma of the lumbar spine and literature review. Front Med (Lausanne). 2024;11:1507716. PMID: 39911670. keyword: acute promyelocytic leukemia
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